Articles Accessed Most Frequently

These are the Top 20 Papers (by download) for the 30 days preceding May 15, 2008. You can see the summaries if you are registered, or full text and PDFs if you have subscribed.

1.  AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
Dana M. Gwinn, David B. Shackelford, Daniel F. Egan, Maria M. Mihaylova, Annabelle Mery, Debbie S. Vasquez, Benjamin E. Turk and Reuben J. Shaw
[Summary]  [Fulltext]  [PDF] 
Apr 25, 2008 
30 (2)
2.  The Metastasis-Associated Gene Prl-3 Is a p53 Target Involved in Cell-Cycle Regulation
Shashwati Basak, Suzanne B.R. Jacobs, Adam J. Krieg, Navneeta Pathak, Qi Zeng, Philipp Kaldis, Amato J. Giaccia and Laura D. Attardi
[Summary]  [Fulltext]  [PDF] 
May 09, 2008 
30 (3)
3.  FACT-Mediated Exchange of Histone Variant H2AX Regulated by Phosphorylation of H2AX and ADP-Ribosylation of Spt16
Kyu Heo, Hyunjung Kim, Si Ho Choi, Jongkyu Choi, Kyunghwan Kim, Jiafeng Gu, Michael R. Lieber, Allen S. Yang and Woojin An
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
30 (1)
4.  IAPs: What's in a Name?
Srinivasa M. Srinivasula and Jonathan D. Ashwell
[Summary]  [Fulltext]  [PDF] 
Apr 25, 2008 
30 (2)
5.  Division of Labor at the Eukaryotic Replication Fork
Stephanie A. Nick McElhinny, Dmitry A. Gordenin, Carrie M. Stith, Peter M.J. Burgers and Thomas A. Kunkel
[Summary]  [Fulltext]  [PDF] 
Apr 25, 2008 
30 (2)
6.  Colocalization of Sensors Is Sufficient to Activate the DNA Damage Checkpoint in the Absence of Damage
Carla Yaneth Bonilla, Justine Amy Melo and David Paul Toczyski
[Summary]  [Fulltext]  [PDF] 
May 09, 2008 
30 (3)
7.  PKBα/Akt1 Acts Downstream of DNA-PK in the DNA Double-Strand Break Response and Promotes Survival
Lana Bozulic, Banu Surucu, Debby Hynx and Brian A. Hemmings
[Summary]  [Fulltext]  [PDF] 
Apr 25, 2008 
30 (2)
8.  Toward a Comprehensive Temperature-Sensitive Mutant Repository of the Essential Genes of Saccharomyces cerevisiae
Shay Ben-Aroya, Candice Coombes, Teresa Kwok, Kathryn A. O'Donnell, Jef D. Boeke and Philip Hieter
[Summary]  [Fulltext]  [PDF] 
Apr 25, 2008 
30 (2)
9.  The DNA Damage Response: Ten Years After
J. Wade Harper and Stephen J. Elledge
[Summary]  [Fulltext]  [PDF] 
Dec 14, 2007 
28 (5)
10.  Argonaute Proteins: Mediators of RNA Silencing
Lasse Peters and Gunter Meister
[Summary]  [Fulltext]  [PDF] 
Jun 08, 2007 
26 (5)
11.  The Splicing Factor SF2/ASF Regulates Translation Initiation by Enhancing Phosphorylation of 4E-BP1
Gracjan Michlewski, Jeremy R. Sanford and Javier F. Cáceres
[Summary]  [Fulltext]  [PDF] 
Apr 25, 2008 
30 (2)
12.  The Age of Crosstalk: Phosphorylation, Ubiquitination, and Beyond
Tony Hunter
[Summary]  [Fulltext]  [PDF] 
Dec 14, 2007 
28 (5)
13.  An ARS Element Inhibits DNA Replication through a SIR2-Dependent Mechanism
Amber Crampton, FuJung Chang, Donald L. Pappas, Ryan L. Frisch and Michael Weinreich
[Summary]  [Fulltext]  [PDF] 
Apr 25, 2008 
30 (2)
14.  DNA Polymerases at the Replication Fork in Eukaryotes
Bruce Stillman
[Summary]  [Fulltext]  [PDF] 
May 09, 2008 
30 (3)
15.  Recurrent Initiation: A Mechanism for Triggering p53 Pulses in Response to DNA Damage
Eric Batchelor, Caroline S. Mock, Irun Bhan, Alexander Loewer and Galit Lahav
[Summary]  [Fulltext]  [PDF] 
May 09, 2008 
30 (3)
16.  Glycolytic Enzyme GAPDH Promotes Peroxide Stress Signaling through Multistep Phosphorelay to a MAPK Cascade
Susumu Morigasaki, Koichi Shimada, Aminah Ikner, Mitsuaki Yanagida and Kazuhiro Shiozaki
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
30 (1)
17.  PHAPI, CAS, and Hsp70 Promote Apoptosome Formation by Preventing Apaf-1 Aggregation and Enhancing Nucleotide Exchange on Apaf-1
Hyun-Eui Kim, Xuejun Jiang, Fenghe Du and Xiaodong Wang
[Summary]  [Fulltext]  [PDF] 
Apr 25, 2008 
30 (2)
18.  AMPK and Raptor: Matching Cell Growth to Energy Supply
D. Grahame Hardie
[Summary]  [Fulltext]  [PDF] 
May 09, 2008 
30 (3)
19.  Differential Regulation of the Cellular Response to DNA Double-Strand Breaks in G1
Jacqueline H. Barlow, Michael Lisby and Rodney Rothstein
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
30 (1)
20.  Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase
Krithika Subramanian, Da Jia, Priya Kapoor-Vazirani, Doris R. Powell, Robert E. Collins, Dipali Sharma, Junmin Peng, Xiaodong Cheng and Paula M. Vertino
[Summary]  [Fulltext]  [PDF] 
May 09, 2008 
30 (3)